Activity record

PGDB_A004587

Assay: % DegradationTarget: VAV1QC: standardized
Activity overview

Dmax = 97.1 %

TargetVAV1
Cell lineJurkat
Time24 h
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS002277
PatentWO2026098632A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031194
Compound IDPGDB_C031194
Compound6;6;6;6;6
Source record IDPGDB_C031194
InChIKeyJKMNOXFEJIFJIG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002277
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
Treatment time24 h
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026098632A1
Compound location

6;6;6;6;6

6;6;6;6;6 enlarged structure6;6;6;6;6 location on patent page 22
Activity table
Page 63 · table single