Molecular glue induced ternary complex
23,555

Compounds

Browse collected molecular glue compounds and linked records.

Browse records →
79,287

Activity Records

Compare normalized values with original patent evidence.

Browse records →
2,583

Assays

Review assay systems, readouts and linked activity evidence.

Browse records →
327

Patents

Review patent sources linked to compounds and activities.

Browse records →
115

Targets

Explore target bioentities connected to activity records.

Browse records →
13

E3 Ligases

Browse E3 ligases and complex components linked to activity evidence.

Browse records →
220

Cell Lines

Find cellular context linked to patent activity evidence.

Browse records →
27

Activity Metrics

Scan endpoint metrics such as DC50, IC50, Dmax and Emax.

Browse records →
133

Assignees

Explore assignees linked to patent families, targets and activity evidence.

Browse records →

Evidence you can trace. Data you can trust.

PatGlueDB provides curated molecular glue bioactivity records alongside source patent pages, with the corresponding molecular structures and activity tables highlighted.

Compound location

CC-885

Activity table
WO2022257897A1 page 134 table start
WO2022257897A1 page 135 table end
Source patent evidenceWO2022257897A1CompoundPGDB_C000058 · CC-885ActivityPGDB_A042422 · = 0.653 uMAssayPGDB_AS001868 · degradation · HT-1080Database links8 activities · 4 patents
CompoundPGDB_C000058CC-885
2D structure for PGDB_C000058
ActivityPGDB_A042422Hangzhou Glubio Pharmaceutical
Metric
DC50
Relation
=
Value
0.653
Unit
uM
Target
CSNK1A1
E3
CRBN
Cell line
HT-1080
Assay
cell-based degradation
Conditions
20 h; 10 uM

...