Activity record

PGDB_A007565

Assay: bindingTarget: CRBNQC: standardized
Activity overview

Ki < 0.5 uM

TargetCRBN
E3 ligaseCRBN
Time60 min
Assay / Readoutfluorescence / Ki
Assay IDPGDB_AS001158
PatentWO2022255890A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009984
Compound IDPGDB_C009984
Compound2
Source record IDPGDB_C009984
InChIKeyFANMCGDWWOEBBE-IGCSZOOQSA-N

Assay context

Assay IDPGDB_AS001158
Assay familybinding
Assay systembiochemical
ReadoutKi
Technologyfluorescence
Treatment time60 min
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDWO2022255890A1
Compound location

2

2 enlarged structure2 location on patent page 68
Activity table
Page 68 · table single