Activity record

PGDB_A008364

Assay: % DegradationQC: ambiguous
Activity overview

DC50 <= 50 nM

Cell lineJurkat
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS002078
PatentCN121698875A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024873
Compound IDPGDB_C024873
Compound1145-P2;1145-P2;化合物1145-P2
Source record IDPGDB_C024873
InChIKeyNIQYZMFDGWQRTP-GKOGFXNCSA-N

Assay context

Assay IDPGDB_AS002078
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDCN121698875A
Compound location

1145-P2;1145-P2;化合物1145-P2

1145-P2;1145-P2;化合物1145-P2 enlarged structure1145-P2;1145-P2;化合物1145-P2 location on patent page 53
Activity table
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