Activity record

PGDB_A015615

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 = 10-50 nM

TargetGSPT1
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS000881
PatentCN120865187A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C003413
Compound IDPGDB_C003413
Compound12
Source record IDPGDB_C003413
InChIKeyIXVBXEKOLOUSPE-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000881
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
Detection targetprotein_degradation
TargetGSPT1
E3Not specified

Source evidence

Patent IDCN120865187A
Compound location

12

12 enlarged structure12 location on patent page 10
Activity table
Page 13 · table single