Activity record

PGDB_A022860

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 <= 100 nM

TargetGSPT1
E3 ligaseCRBN
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001857
PatentWO2022219407A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009981
Compound IDPGDB_C009981
Compound75
Source record IDPGDB_C009981
InChIKeyNQTQXQUKCAYGMI-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001857
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TargetGSPT1
E3CRBN

Source evidence

Patent IDWO2022219407A1
Compound location

75

75 enlarged structure75 location on patent page 122
Activity table
Page 185 · table single