Activity record

PGDB_A026997

Assay: % DegradationTarget: BCL6QC: standardized
Activity overview

DC50 = 78 nM

TargetBCL6
Cell lineOCI-LY1
Time12 h
Assay / ReadoutWestern_blot / DC50
Assay IDPGDB_AS001697
PatentWO2025242013A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009167
Compound IDPGDB_C009167
Compound实施例 10
Source record IDPGDB_C009167
InChIKeyUFVAKCVLMCEOMP-IYBDPMFKSA-N

Assay context

Assay IDPGDB_AS001697
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyWestern_blot
Treatment time12 h
TargetBCL6
E3Not specified
Cell lineOCI-LY1

Source evidence

Patent IDWO2025242013A1
Compound location

实施例 10

实施例 10 enlarged structure实施例 10 location on patent page 20
Activity table
Page 21 · table single