Activity record

PGDB_A036048

Assay: % DegradationTarget: GSPT1QC: ambiguous
Activity overview

DC50 < 30 nM

TargetGSPT1
Cell lineNCI-H1155
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS001520
PatentCN119591581A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000695
Compound IDPGDB_C000695
Compound实施例14
Source record IDPGDB_C000695
InChIKeySZYHJXODGCPRIV-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001520
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetGSPT1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDCN119591581A
Compound location

实施例14

实施例14 enlarged structure实施例14 location on patent page 72
Activity table
Page 74 · table single