Activity record

PGDB_A045699

Assay: ternary_complexTarget: SMAD4QC: ambiguous
Activity overview

EC50 = 9 uM

TargetSMAD4
Assay / ReadoutEC50 / ternary_complex
Assay IDPGDB_AS001717
PatentUS20230201173A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C009142
Compound IDPGDB_C009142
CompoundRo-31-8425
Source record IDPGDB_C009142
InChIKeyQQKKPWJFHBFCTH-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001717
Assay familyternary_complex
Assay systembiochemical
ReadoutEC50
TargetSMAD4
E3Not specified

Source evidence

Patent IDUS20230201173A1
Compound location

Ro-31-8425

Ro-31-8425 enlarged structureRo-31-8425 location on patent page 4
Activity table
Page 4 · table single