Activity record

PGDB_A045714

Assay: viabilityTarget: GSPT1QC: standardized
Activity overview

IC50 < 50 nM

TargetGSPT1
Cell lineNCI-H1155
Time72 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS000248
PatentCN119591581A
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000692
Compound IDPGDB_C000692
Compound实施例8
Source record IDPGDB_C000692
InChIKeyIRDDQWCYDVNTAP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000248
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time72 h
Detection targetcell_proliferation
TargetGSPT1
E3Not specified
Cell lineNCI-H1155

Source evidence

Patent IDCN119591581A
Compound location

实施例8

实施例8 enlarged structure实施例8 location on patent page 69
Activity table
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