Activity record

PGDB_A057503

Assay: bindingTarget: CRBNQC: ambiguous
Activity overview

IC50 = 0.141 uM

TargetCRBN
E3 ligaseCRBN
Time15 min
Assay / Readoutfluorescence / IC50
Assay IDPGDB_AS002009
PatentCN120192331A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000698
Compound IDPGDB_C000698
Compound3;3;3;3
Source record IDPGDB_C000698
InChIKeyFMXTVNHQSFYFJU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002009
Assay familybinding
Assay systembiochemical
ReadoutIC50
Technologyfluorescence
Treatment time15 min
TargetCRBN
E3CRBN

Source evidence

Patent IDCN120192331A
Compound location

3;3;3;3

3;3;3;3 enlarged structure3;3;3;3 location on patent page 33
Activity table
Page 41 · table single