Activity record

PGDB_A061222

Assay: % DegradationQC: ambiguous
Activity overview

DC50 <= 50 nM

Cell lineJurkat
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS002078
PatentCN121698875A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024751
Compound IDPGDB_C024751
Compound557;557
Source record IDPGDB_C024751
InChIKeyRFWBJSYPEKNEDF-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002078
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDCN121698875A
Compound location

557;557

557;557 enlarged structure557;557 location on patent page 35
Activity table
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