Activity record

PGDB_A077217

Assay: % DegradationQC: ambiguous
Activity overview

DC50 <= 50 nM

Cell lineJurkat
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS002078
PatentCN121698875A
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024758
Compound IDPGDB_C024758
Compound771;771;771
Source record IDPGDB_C024758
InChIKeyHLDPJQHACBTJGU-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002078
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDCN121698875A
Compound location

771;771;771

771;771;771 enlarged structure771;771;771 location on patent page 40
Activity table
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