PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN117946075A

AssigneeHangzhou Arnold Biomedical Technology

TitleCyclin K degraders

Family ID85322521

Family members13

Filing year2022

Publication date2024-04-30

JurisdictionCN

Compounds67

Activity records68

Assays1

Activity compounds and values

Activity records

68 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	193	nM	-	—	CCNK	-	HGC-27	PGDB_A007585	PGDB_C006709	PGDB_AS000524	View
IC50	-	=	341	nM	-	—	CCNK	-	HGC-27	PGDB_A009077	PGDB_C006679	PGDB_AS000524	View
IC50	-	=	410	nM	-	—	CCNK	-	HGC-27	PGDB_A012336	PGDB_C006722	PGDB_AS000524	View
IC50	-	=	89	nM	-	—	CCNK	-	HGC-27	PGDB_A013093	PGDB_C006699	PGDB_AS000524	View
IC50	-	=	281	nM	-	—	CCNK	-	HGC-27	PGDB_A013498	PGDB_C006721	PGDB_AS000524	View
IC50	-	=	406	nM	-	—	CCNK	-	HGC-27	PGDB_A013701	PGDB_C006707	PGDB_AS000524	View
IC50	-	=	39	nM	-	—	CCNK	-	HGC-27	PGDB_A014267	PGDB_C006716	PGDB_AS000524	View
IC50	-	=	48	nM	-	—	CCNK	-	HGC-27	PGDB_A015918	PGDB_C006728	PGDB_AS000524	View
IC50	-	=	266	nM	-	—	CCNK	-	HGC-27	PGDB_A016063	PGDB_C006680	PGDB_AS000524	View
IC50	-	=	108	nM	-	—	CCNK	-	HGC-27	PGDB_A019961	PGDB_C006710	PGDB_AS000524	View
IC50	-	=	63	nM	-	—	CCNK	-	HGC-27	PGDB_A020879	PGDB_C006711	PGDB_AS000524	View
IC50	-	=	49	nM	-	—	CCNK	-	HGC-27	PGDB_A021092	PGDB_C006701	PGDB_AS000524	View
IC50	-	=	77	nM	-	—	CCNK	-	HGC-27	PGDB_A021555	PGDB_C006693	PGDB_AS000524	View
IC50	-	=	307	nM	-	—	CCNK	-	HGC-27	PGDB_A027589	PGDB_C006674	PGDB_AS000524	View
IC50	-	=	45	nM	-	—	CCNK	-	HGC-27	PGDB_A029358	PGDB_C006727	PGDB_AS000524	View
IC50	-	=	281	nM	-	—	CCNK	-	HGC-27	PGDB_A029873	PGDB_C006675	PGDB_AS000524	View
IC50	-	=	197	nM	-	—	CCNK	-	HGC-27	PGDB_A029936	PGDB_C006724	PGDB_AS000524	View
IC50	-	=	446	nM	-	—	CCNK	-	HGC-27	PGDB_A030224	PGDB_C006692	PGDB_AS000524	View
IC50	-	=	202	nM	-	—	CCNK	-	HGC-27	PGDB_A030990	PGDB_C006683	PGDB_AS000524	View
IC50	-	=	25	nM	-	—	CCNK	-	HGC-27	PGDB_A031105	PGDB_C006705	PGDB_AS000524	View

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