PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN118206535A

AssigneeHangzhou Arnold Biomedical Technology

TitleCyclin K degrading agent and its application

Family ID91447802

Family members6

Filing year2023

Publication date2024-06-18

JurisdictionCN

Compounds79

Activity records128

Assays2

Activity compounds and values

Activity records

128 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	48	nM	-	—	CCNK	-	NCI-N87	PGDB_A007905	PGDB_C006764	PGDB_AS002215	View
IC50	-	=	14	nM	-	—	CCNK	-	HGC-27	PGDB_A009369	PGDB_C006813	PGDB_AS000326	View
IC50	-	=	32	nM	-	—	CCNK	-	HGC-27	PGDB_A009406	PGDB_C006788	PGDB_AS000326	View
IC50	-	=	13	nM	-	—	CCNK	-	HGC-27	PGDB_A009966	PGDB_C006782	PGDB_AS000326	View
IC50	-	=	257	nM	-	—	CCNK	-	HGC-27	PGDB_A010362	PGDB_C006800	PGDB_AS000326	View
IC50	-	=	454	nM	-	—	CCNK	-	HGC-27	PGDB_A010901	PGDB_C006761	PGDB_AS000326	View
IC50	-	=	15	nM	-	—	CCNK	-	NCI-N87	PGDB_A011582	PGDB_C006772	PGDB_AS002215	View
IC50	-	=	120	nM	-	—	CCNK	-	NCI-N87	PGDB_A011927	PGDB_C006781	PGDB_AS002215	View
IC50	-	=	10	nM	-	—	CCNK	-	NCI-N87	PGDB_A012251	PGDB_C006788	PGDB_AS002215	View
IC50	-	=	3.1	nM	-	—	CCNK	-	NCI-N87	PGDB_A012533	PGDB_C006758	PGDB_AS002215	View
IC50	-	=	9	nM	-	—	CCNK	-	NCI-N87	PGDB_A012561	PGDB_C006802	PGDB_AS002215	View
IC50	-	=	266	nM	-	—	CCNK	-	HGC-27	PGDB_A013189	PGDB_C006797	PGDB_AS000326	View
IC50	-	=	510	nM	-	—	CCNK	-	HGC-27	PGDB_A013263	PGDB_C006799	PGDB_AS000326	View
IC50	-	=	5.3	nM	-	—	CCNK	-	NCI-N87	PGDB_A013427	PGDB_C006813	PGDB_AS002215	View
IC50	-	=	13	nM	-	—	CCNK	-	NCI-N87	PGDB_A014706	PGDB_C006755	PGDB_AS002215	View
IC50	-	=	8	nM	-	—	CCNK	-	HGC-27	PGDB_A014863	PGDB_C006804	PGDB_AS000326	View
IC50	-	=	58	nM	-	—	CCNK	-	NCI-N87	PGDB_A015528	PGDB_C006769	PGDB_AS002215	View
IC50	-	=	2	nM	-	—	CCNK	-	NCI-N87	PGDB_A015825	PGDB_C006810	PGDB_AS002215	View
IC50	-	=	89	nM	-	—	CCNK	-	HGC-27	PGDB_A017666	PGDB_C006795	PGDB_AS000326	View
IC50	-	=	68	nM	-	—	CCNK	-	HGC-27	PGDB_A018177	PGDB_C006776	PGDB_AS000326	View

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