PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberCN118955493

AssigneeGuangdong Pharmaceutical University

TitleA novel CCNK molecular glue degrading agent, preparation method thereof and use thereof as a medicine

Family ID93398041

Family members2

Filing year2024

Publication date2024-11-15

JurisdictionCN

Compounds39

Activity records117

Assays3

Activity compounds and values

Activity records

117 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
IC50	-	=	2.25	uM	-	—	CCNK	-	MDA-MB-231	PGDB_A007027	PGDB_C006856	PGDB_AS001422	View
IC50	-	>	4	uM	-	—	CCNK	-	A549	PGDB_A007084	PGDB_C006862	PGDB_AS002241	View
IC50	-	>	4	uM	-	—	CCNK	-	MDA-MB-231	PGDB_A007376	PGDB_C006875	PGDB_AS001422	View
IC50	-	>	4	uM	-	—	CCNK	-	HepG2	PGDB_A007972	PGDB_C006848	PGDB_AS001525	View
IC50	-	=	0.741	uM	-	—	CCNK	-	HepG2	PGDB_A008702	PGDB_C006865	PGDB_AS001525	View
IC50	-	>	4	uM	-	—	CCNK	-	A549	PGDB_A008922	PGDB_C006848	PGDB_AS002241	View
IC50	-	=	2.018	uM	-	—	CCNK	-	A549	PGDB_A009741	PGDB_C006851	PGDB_AS002241	View
IC50	-	=	0.41	uM	-	—	CCNK	-	A549	PGDB_A009968	PGDB_C006861	PGDB_AS002241	View
IC50	-	=	0.966	uM	-	—	CCNK	-	MDA-MB-231	PGDB_A010651	PGDB_C006860	PGDB_AS001422	View
IC50	-	>	4	uM	-	—	CCNK	-	HepG2	PGDB_A010793	PGDB_C006877	PGDB_AS001525	View
IC50	-	>	4	uM	-	—	CCNK	-	A549	PGDB_A011362	PGDB_C006846	PGDB_AS002241	View
IC50	-	>	4	uM	-	—	CCNK	-	A549	PGDB_A011644	PGDB_C006854	PGDB_AS002241	View
IC50	-	>	4	uM	-	—	CCNK	-	A549	PGDB_A012427	PGDB_C006863	PGDB_AS002241	View
IC50	-	>	4	uM	-	—	CCNK	-	A549	PGDB_A013076	PGDB_C006880	PGDB_AS002241	View
IC50	-	>	4	uM	-	—	CCNK	-	HepG2	PGDB_A013646	PGDB_C006851	PGDB_AS001525	View
IC50	-	>	4	uM	-	—	CCNK	-	HepG2	PGDB_A013898	PGDB_C006845	PGDB_AS001525	View
IC50	-	>	4	uM	-	—	CCNK	-	HepG2	PGDB_A014300	PGDB_C006871	PGDB_AS001525	View
IC50	-	>	4	uM	-	—	CCNK	-	HepG2	PGDB_A014360	PGDB_C006880	PGDB_AS001525	View
IC50	-	>	4	uM	-	—	CCNK	-	MDA-MB-231	PGDB_A014983	PGDB_C006871	PGDB_AS001422	View
IC50	-	=	2.576	uM	-	—	CCNK	-	MDA-MB-231	PGDB_A016228	PGDB_C006862	PGDB_AS001422	View

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