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Patent
CN119325469A
451 compounds1,742 activity records4 assays
Patent summary
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | Ymin | - | = | 8.183127473 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A007133 | PGDB_C023462 | PGDB_AS000567 | View |
 | EC50 | - | = | 0.001609494 | uM | - | — | WEE1 | - | MKN45 | PGDB_A007154 | PGDB_C023390 | PGDB_AS001345 | View |
 | EC50 | - | = | 0.065544 | uM | - | — | WEE1 | - | HEK293T | PGDB_A007156 | PGDB_C023181 | PGDB_AS001487 | View |
 | % Degradation | - | = | 68 | % | Concentration range: 10 uM | 4 h | WEE1 | - | HEK293T | PGDB_A007166 | PGDB_C023371 | PGDB_AS001384 | View |
 | Ymin | - | = | 7.53 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A007261 | PGDB_C023368 | PGDB_AS000567 | View |
 | % Degradation | - | = | 65.80090714 | % | Concentration range: 10 uM | 4 h | WEE1 | - | HEK293T | PGDB_A007270 | PGDB_C023519 | PGDB_AS001384 | View |
 | % Degradation | - | = | 72.0959816 | % | Concentration range: 10 uM | 4 h | WEE1 | - | HEK293T | PGDB_A007297 | PGDB_C023448 | PGDB_AS001384 | View |
 | Ymin | - | = | 8.59 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A007360 | PGDB_C023313 | PGDB_AS000567 | View |
 | EC50 | - | = | 0.013813886 | uM | - | — | WEE1 | - | MKN45 | PGDB_A007383 | PGDB_C023528 | PGDB_AS001345 | View |
 | EC50 | - | = | 0.022697587 | uM | - | — | WEE1 | - | MKN45 | PGDB_A007420 | PGDB_C023457 | PGDB_AS001345 | View |
| EC50 | - | = | 0.013077475 | uM | - | — | WEE1 | - | HEK293T | PGDB_A007479 | PGDB_C023457 | PGDB_AS001487 | View |
 | EC50 | - | = | 0.004468 | uM | - | — | WEE1 | - | HEK293T | PGDB_A007492 | PGDB_C023150 | PGDB_AS001487 | View |
 | EC50 | - | = | 0.005382 | uM | - | — | WEE1 | - | HEK293T | PGDB_A007504 | PGDB_C023446 | PGDB_AS001487 | View |
 | Ymin | - | = | 12.12 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A007509 | PGDB_C023220 | PGDB_AS000567 | View |
 | EC50 | - | = | 10 | uM | - | — | WEE1 | - | HEK293T | PGDB_A007543 | PGDB_C023228 | PGDB_AS001487 | View |
 | EC50 | - | = | 0.001285412 | uM | - | — | WEE1 | - | MKN45 | PGDB_A007593 | PGDB_C023369 | PGDB_AS001345 | View |
 | EC50 | - | = | 0.003269162 | uM | - | — | WEE1 | - | HEK293T | PGDB_A007615 | PGDB_C023486 | PGDB_AS001487 | View |
 | Ymin | - | = | 19.68 | % | Concentration series: 1 uM, 10 uM | 120 h | WEE1 | - | MKN45 | PGDB_A007632 | PGDB_C023179 | PGDB_AS000567 | View |
 | EC50 | - | = | 0.003325333 | uM | - | — | WEE1 | - | HEK293T | PGDB_A007667 | PGDB_C023302 | PGDB_AS001487 | View |
 | EC50 | - | = | 0.030351345 | uM | - | — | WEE1 | - | MKN45 | PGDB_A007675 | PGDB_C023124 | PGDB_AS001345 | View |