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Patent
CN121449584A
5 compounds11 activity records4 assays
Patent summary
Activity compounds and values
Activity records
| Structure | Control | Value | Concentration | Time | Record ID | Compound | Assay | Details | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
 | % Inhibition | - | = | 12.86 | % | Concentration context: 10 uM | - | KCNH2 | - | HEK293 | PGDB_A025315 | PGDB_C003418 | PGDB_AS001701 | View |
 | IC50 | - | = | 41.25 | nM | - | — | - | - | MDA-MB-468 | PGDB_A030869 | PGDB_C003415 | PGDB_AS002234 | View |
| % Inhibition | - | = | 10.41 | % | Concentration context: 3 uM | 5 min | KCNH2 | - | HEK293 | PGDB_A031604 | PGDB_C003418 | PGDB_AS000243 | View |
 | IC50 | - | = | 6.385 | nM | - | — | - | - | NCI-H1155 | PGDB_A033989 | PGDB_C003416 | PGDB_AS001856 | View |
 | IC50 | - | = | 2.839 | nM | - | — | - | - | NCI-H1155 | PGDB_A034401 | PGDB_C003419 | PGDB_AS001856 | View |
 | IC50 | - | = | 9.845 | nM | - | — | - | - | NCI-H1155 | PGDB_A041406 | PGDB_C003417 | PGDB_AS001856 | View |
| IC50 | - | = | 27.82 | nM | - | — | - | - | MDA-MB-468 | PGDB_A051768 | PGDB_C003416 | PGDB_AS002234 | View |
| IC50 | - | = | 14.75 | nM | - | — | - | - | MDA-MB-468 | PGDB_A054254 | PGDB_C003417 | PGDB_AS002234 | View |
| IC50 | - | = | 12.82 | nM | - | — | - | - | NCI-H1155 | PGDB_A068618 | PGDB_C003415 | PGDB_AS001856 | View |
| IC50 | - | = | 9.571 | nM | - | — | - | - | MDA-MB-468 | PGDB_A073709 | PGDB_C003418 | PGDB_AS002234 | View |
| IC50 | - | = | 1.569 | nM | - | — | - | - | NCI-H1155 | PGDB_A076979 | PGDB_C003418 | PGDB_AS001856 | View |