PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2025188579A8

AssigneeMassachusetts Institute Of Technology

TitleTox inhibitors and molecular glues, methods of use thereof, and kits comprising the same

Family ID95365139

Family members2

Filing year2025

Publication date2025-10-02

JurisdictionWO

Compounds11

Activity records47

Assays10

Activity compounds and values

Activity records

47 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
CC50	-	=	13.4	uM	-	—	TOX	-	Jurkat	PGDB_A010820	PGDB_C011412	PGDB_AS001168	View
CC50	-	=	11.5	uM	-	—	TOX	-	Hut78	PGDB_A011551	PGDB_C011411	PGDB_AS001427	View
CC50	-	=	49.9	uM	-	—	TOX	-	Hut78	PGDB_A012008	PGDB_C011414	PGDB_AS001427	View
CC50	-	=	37.9	uM	-	—	TOX	-	MOLT-4	PGDB_A014812	PGDB_C011409	PGDB_AS002130	View
CC50	-	=	12.3	uM	-	—	TOX	-	HBP-ALL	PGDB_A014874	PGDB_C011412	PGDB_AS002116	View
CC50	-	=	4.1	uM	-	—	TOX	-	Hut78	PGDB_A016706	PGDB_C011412	PGDB_AS001427	View
CC50	-	=	0.9	uM	-	—	TOX	-	HH	PGDB_A016721	PGDB_C011415	PGDB_AS000066	View
CC50	-	=	2.4	uM	-	—	TOX	-	HH	PGDB_A016917	PGDB_C011405	PGDB_AS001040	View
CC50	-	=	62.9	uM	-	—	TOX	-	HH	PGDB_A020597	PGDB_C011409	PGDB_AS001040	View
CC50	-	=	8.1	uM	-	—	TOX	-	HBP-ALL	PGDB_A022039	PGDB_C011413	PGDB_AS002116	View
CC50	-	=	3.3	uM	-	—	TOX	-	HBP-ALL	PGDB_A022936	PGDB_C011415	PGDB_AS002116	View
CC50	-	=	15.2	uM	-	—	TOX	-	HH	PGDB_A023169	PGDB_C011411	PGDB_AS000066	View
CC50	-	=	20.2	uM	-	—	TOX	-	HBP-ALL	PGDB_A023296	PGDB_C011411	PGDB_AS002116	View
CC50	-	=	23.2	uM	-	—	TOX	-	HBP-ALL	PGDB_A024340	PGDB_C011408	PGDB_AS000585	View
CC50	-	=	18.6	uM	-	—	TOX	-	Jurkat	PGDB_A025571	PGDB_C011410	PGDB_AS001168	View
CC50	-	=	5.9	uM	-	—	TOX	-	MOLT-4	PGDB_A026729	PGDB_C011412	PGDB_AS001251	View
CC50	-	=	2.2	uM	-	—	TOX	-	Jurkat	PGDB_A029540	PGDB_C011415	PGDB_AS001168	View
CC50	-	=	4.7	uM	-	—	TOX	-	HBP-ALL	PGDB_A031472	PGDB_C011414	PGDB_AS002116	View
CC50	-	=	27	uM	-	—	TOX	-	Hut78	PGDB_A031926	PGDB_C011405	PGDB_AS001719	View
CC50	-	=	3.2	uM	-	—	TOX	-	MOLT-4	PGDB_A033467	PGDB_C011413	PGDB_AS001251	View

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