Activity record

PGDB_A000744

Assay: biochemicalTarget: VAV1QC: ambiguous
Activity overview

EC50 = 100-1000 nM

TargetVAV1
E3 ligaseCRBN
Assay / ReadoutHTRF / EC50
Assay IDPGDB_AS000672
PatentWO2026119245A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C032076
Compound IDPGDB_C032076
Compound实施例 2
Source record IDPGDB_C032076
InChIKeyBNPXZVKFXBHEKC-DEOSSOPVSA-N

Assay context

Assay IDPGDB_AS000672
Assay familybiochemical
Assay systembiochemical
ReadoutEC50
TechnologyHTRF
TargetCRBN | DDB1
E3CRBN | DDB1

Source evidence

Patent IDWO2026119245A1
Compound location

实施例 2

实施例 2 enlarged structure实施例 2 location on patent page 38
Activity table
Page 63 · table single