PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2026119245A1

AssigneeBeijing Earthwise Technology Co Ltd

TitleCOMPOUNDS FOR DEGRADING HUMAN PROTOONCOGENE VAV1 PROTEIN (VAV1)

Family IDunresolved_family_WO2026119245A1

Family members1

Filing year2025

Publication date2026-06-11

JurisdictionWO

Compounds190

Activity records194

Assays2

Activity compounds and values

Activity records

194 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000033	PGDB_C032202	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000104	PGDB_C032078	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000149	PGDB_C032218	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000185	PGDB_C032215	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000243	PGDB_C032115	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000397	PGDB_C032169	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000595	PGDB_C032126	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000606	PGDB_C032164	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000624	PGDB_C032176	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000643	PGDB_C032109	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000685	PGDB_C032213	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000708	PGDB_C032108	PGDB_AS001875	View
EC50	-	=	100-1000	nM	-	—	VAV1	CRBN	-	PGDB_A000744	PGDB_C032076	PGDB_AS000672	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000771	PGDB_C032106	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000798	PGDB_C032124	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000838	PGDB_C032227	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000888	PGDB_C032092	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000891	PGDB_C032211	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A000957	PGDB_C032166	PGDB_AS001875	View
DC50	-	<	100	nM	-	—	VAV1	-	-	PGDB_A001160	PGDB_C032099	PGDB_AS001875	View

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