Activity record

PGDB_A000766

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 0.5 nM

E3 ligaseCRBN
Cell lineSW620
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001786
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031950
Compound IDPGDB_C031950
CompoundI-10;I-10
Source record IDPGDB_C031950
InChIKeyALBGNPALBHMPJS-JUTMFZQISA-N

Assay context

Assay IDPGDB_AS001786
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineSW620
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-10;I-10

I-10;I-10 enlarged structureI-10;I-10 location on patent page 248
Activity table
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