Activity record

PGDB_A001129

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 6.4 nM

E3 ligaseCRBN
Cell lineLOVO
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000484
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031956
Compound IDPGDB_C031956
CompoundI-16
Source record IDPGDB_C031956
InChIKeyZJVJHHJRNMBREP-GNXBRKQNSA-N

Assay context

Assay IDPGDB_AS000484
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineLOVO
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-16

I-16 enlarged structureI-16 location on patent page 250
Activity table
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