Activity record

PGDB_A001525

Assay: viabilityTarget: VAV1QC: standardized
Activity overview

IC50 <= 1 nM

TargetVAV1
Cell lineprimary T cells
Time24 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000754
PatentWO2026114367A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031775
Compound IDPGDB_C031775
Compound化合物15
Source record IDPGDB_C031775
InChIKeySZGLGDMMVFPAPD-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000754
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time24 h
TargetVAV1
E3Not specified
Cell lineprimary T cells
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物15

化合物15 enlarged structure化合物15 location on patent page 92
Activity table
Page 206 · table single