Activity record

PGDB_A001700

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 50 %

TargetNEK7
Cell lineCAL-51
ConcentrationConcentration series: 1 uM, 0.05 nM
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000358
PatentWO2026099466A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031323
Compound IDPGDB_C031323
Compound125
Source record IDPGDB_C031323
InChIKeyVDIQRBGCQSEKPW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000358
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration series: 1 uM, 0.05 nM
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2026099466A1
Compound location

125

125 enlarged structure125 location on patent page 58
Activity table
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Page 187 · table end