Activity record

PGDB_A001827

Assay: % DegradationTarget: VAV1QC: standardized
Activity overview

Dmax = 84 %

TargetVAV1
Cell lineJurkat
Concentration0.08 nM
Assay / ReadoutHTRF / Dmax
Assay IDPGDB_AS000246
PatentWO2026119120A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C032002
Compound IDPGDB_C032002
Compound52;52;化合物52
Source record IDPGDB_C032002
InChIKeyMACBYRPWVNYOPP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000246
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
TechnologyHTRF
Concentration0.08 nM
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026119120A1
Compound location

52;52;化合物52

52;52;化合物52 enlarged structure52;52;化合物52 location on patent page 30
Activity table
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