PatGlueDB | Molecular Glue Patent Bioactivity Database

Patent summary

Publication numberWO2026119120A1

AssigneeChangchun Genescience Pharmaceutical Co Ltd

TitlePIPERIDINEDIONE COMPOUND, PREPARATION METHOD THEREFOR, PHARMACEUTICAL COMPOSITION COMPRISING COMPOUND, AND USE THEREOF

Family IDunresolved_family_WO2026119120A1

Family members1

Filing year2025

Publication date2026-06-11

JurisdictionWO

Compounds78

Activity records160

Assays4

Activity compounds and values

Activity records

160 records

	Control		Value		Concentration	Time				Record ID	Compound	Assay	Details
DC50	-	=	2	nM	-	—	VAV1	-	-	PGDB_A000026	PGDB_C032005	PGDB_AS001984	View
DC50	-	=	4.2	nM	-	—	VAV1	-	-	PGDB_A000043	PGDB_C032057	PGDB_AS001984	View
Dmax	-	=	96.9	%	0.02 nM	-	VAV1	-	-	PGDB_A000096	PGDB_C032056	PGDB_AS000657	View
Dmax	-	=	90.8	%	0.02 nM	-	VAV1	-	-	PGDB_A000255	PGDB_C009245	PGDB_AS000657	View
Dmax	-	=	92.5	%	0.02 nM	-	VAV1	-	-	PGDB_A000317	PGDB_C032004	PGDB_AS000657	View
DC50	-	=	4.7	nM	-	—	VAV1	-	-	PGDB_A000338	PGDB_C024751	PGDB_AS001984	View
DC50	-	=	3	nM	-	—	VAV1	-	-	PGDB_A000372	PGDB_C032042	PGDB_AS001984	View
Dmax	-	=	94.8	%	0.02 nM	-	VAV1	-	-	PGDB_A000378	PGDB_C032002	PGDB_AS000657	View
Dmax	-	=	95.8	%	0.02 nM	-	VAV1	-	-	PGDB_A000385	PGDB_C032063	PGDB_AS000657	View
DC50	-	=	5.9	nM	-	—	VAV1	-	-	PGDB_A000433	PGDB_C009245	PGDB_AS001984	View
DC50	-	=	1.1	nM	-	—	VAV1	-	-	PGDB_A000463	PGDB_C032053	PGDB_AS001984	View
Dmax	-	=	95.7	%	0.02 nM	-	VAV1	-	-	PGDB_A000566	PGDB_C032067	PGDB_AS000657	View
Dmax	-	=	91.9	%	0.02 nM	-	VAV1	-	-	PGDB_A000572	PGDB_C032026	PGDB_AS000657	View
DC50	-	=	42	nM	-	—	VAV1	-	-	PGDB_A000631	PGDB_C032012	PGDB_AS001984	View
Dmax	-	=	94.8	%	0.02 nM	-	VAV1	-	-	PGDB_A000687	PGDB_C032069	PGDB_AS000657	View
DC50	-	=	11.1	nM	-	—	VAV1	-	-	PGDB_A000726	PGDB_C032063	PGDB_AS001984	View
DC50	-	=	2.3	nM	-	—	VAV1	-	-	PGDB_A000836	PGDB_C032041	PGDB_AS001984	View
DC50	-	=	4.8	nM	-	—	VAV1	-	-	PGDB_A001005	PGDB_C024792	PGDB_AS001984	View
DC50	-	=	5.8	nM	-	—	VAV1	-	-	PGDB_A001011	PGDB_C032040	PGDB_AS001984	View
DC50	-	=	2.7	nM	-	—	VAV1	-	-	PGDB_A001117	PGDB_C032067	PGDB_AS001984	View

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