Activity record

PGDB_A002169

Assay: % DegradationTarget: VAV1QC: standardized
Activity overview

DC50 = 2.5 nM

TargetVAV1
Cell lineJurkat
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS000531
PatentWO2026098637A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031196
Compound IDPGDB_C031196
Compound2
Source record IDPGDB_C031196
InChIKeyBCFIWFZCWRDYFQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000531
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026098637A1
Compound location

2

2 enlarged structure2 location on patent page 42
Activity table
Page 98 · table single