Activity record

PGDB_A002453

Assay: viabilityTarget: VAV1QC: standardized
Activity overview

IC50 <= 1 nM

TargetVAV1
Cell lineprimary T cells
Time24 h
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000754
PatentWO2026114367A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031755
Compound IDPGDB_C031755
Compound化合物25
Source record IDPGDB_C031755
InChIKeyYQVSHZHAGYTYCW-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000754
Assay familyviability
Assay systemcell_based
ReadoutIC50
Treatment time24 h
TargetVAV1
E3Not specified
Cell lineprimary T cells
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物25

化合物25 enlarged structure化合物25 location on patent page 98
Activity table
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