Activity record

PGDB_A002563

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 0.9 nM

E3 ligaseCRBN
Cell lineSW620
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001786
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031959
Compound IDPGDB_C031959
CompoundI-19
Source record IDPGDB_C031959
InChIKeyIPXNHGAAZUWXFU-QUKDQQMVSA-N

Assay context

Assay IDPGDB_AS001786
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineSW620
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-19

I-19 enlarged structureI-19 location on patent page 336
Activity table
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