Activity record

PGDB_A002617

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 = 0.35 nM

TargetVAV1
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS000395
PatentWO2026103798A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031331
Compound IDPGDB_C031331
Compound实施例 6
Source record IDPGDB_C031331
InChIKeyDMVKGAYOFLGHPG-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000395
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Detection targetprotein_degradation
TargetVAV1
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026103798A1
Compound location

实施例 6

实施例 6 enlarged structure实施例 6 location on patent page 68
Activity table
Page 90 · table single