Activity record

PGDB_A003018

Assay: viabilityTarget: VAV1QC: ambiguous
Activity overview

IC50 <= 1 nM

TargetVAV1
Cell lineprimaryT
Time96 h
Assay / Readoutluminescence / IC50
Assay IDPGDB_AS002534
PatentWO2026114367A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031784
Compound IDPGDB_C031784
Compound化合物52
Source record IDPGDB_C031784
InChIKeyMIPOXOBXEFVNKM-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS002534
Assay familyviability
Assay systemcell_based
ReadoutIC50
Technologyluminescence
Treatment time96 h
Detection target% Cell viability
TargetVAV1
E3Not specified
Cell lineprimaryT
OrganismHomo sapiens

Source evidence

Patent IDWO2026114367A1
Compound location

化合物52

化合物52 enlarged structure化合物52 location on patent page 113
Activity table
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