Activity record

PGDB_A003593

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 21.8 nM

E3 ligaseCRBN
Cell lineLOVO
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000484
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031964
Compound IDPGDB_C031964
CompoundI-24
Source record IDPGDB_C031964
InChIKeyYTOBXJPIOSKEAH-JKDZDMHUSA-N

Assay context

Assay IDPGDB_AS000484
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineLOVO
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-24

I-24 enlarged structureI-24 location on patent page 337
Activity table
Page 300 · table start
Page 301 · table end