Activity record

PGDB_A003755

Assay: % DegradationTarget: VAV1QC: standardized
Activity overview

DC50 = 2.9 nM

TargetVAV1
Cell lineJurkat
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS000531
PatentWO2026098637A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031199
Compound IDPGDB_C031199
Compound12;12;12;12;12;12
Source record IDPGDB_C031199
InChIKeyYWIIQRUOHYBVSB-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000531
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026098637A1
Compound location

12;12;12;12;12;12

12;12;12;12;12;12 enlarged structure12;12;12;12;12;12 location on patent page 31
Activity table
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