Activity record

PGDB_A003768

Assay: % DegradationTarget: ARQC: ambiguous
Activity overview

degradation = 59 %

TargetAR
Cell lineVCaP
Concentration5 nM
Assay / Readoutfluorescence / % Degradation
Assay IDPGDB_AS001281
PatentWO2026061104A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C030090
Compound IDPGDB_C030090
CompoundAR-P-221
Source record IDPGDB_C030090
InChIKeyALCJRHQAPGIYKB-UFNASBJGSA-N

Assay context

Assay IDPGDB_AS001281
Assay family% Degradation
Assay systemcell_based
Readout% Degradation
Technologyfluorescence
Concentration5 nM
Detection targetprotein_degradation
TargetAR
E3Not specified
Cell lineVCaP
OrganismHomo sapiens

Source evidence

Patent IDWO2026061104A1
Compound location

AR-P-221

AR-P-221 enlarged structureAR-P-221 location on patent page 179
Activity table
Page 269 · table single