Activity record

PGDB_A003967

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 <= 100 nM

TargetVAV1
Cell lineREC-1
Time24 h
Assay / ReadoutDC50 / % Degradation
Assay IDPGDB_AS002449
PatentWO2026103798A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031400
Compound IDPGDB_C031400
Compound实施例 61
Source record IDPGDB_C031400
InChIKeyUTIMQMZDHSSFRR-MAUKXSAKSA-N

Assay context

Assay IDPGDB_AS002449
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Treatment time24 h
TargetVAV1
E3Not specified
Cell lineREC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2026103798A1
Compound location

实施例 61

实施例 61 enlarged structure实施例 61 location on patent page 79
Activity table
Page 88 · table start
Page 89 · table end