Activity record

PGDB_A004828

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 0.7 nM

E3 ligaseCRBN
Cell lineSW620
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS001786
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031976
Compound IDPGDB_C031976
CompoundI-36;I-36
Source record IDPGDB_C031976
InChIKeyKGWYXOVJAHNVRU-ZUTXJMHQSA-N

Assay context

Assay IDPGDB_AS001786
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineSW620
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-36;I-36

I-36;I-36 enlarged structureI-36;I-36 location on patent page 267
Activity table
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