Activity record

PGDB_A004984

Assay: % DegradationTarget: NEK7QC: ambiguous
Activity overview

Dmax = 81 %

TargetNEK7
Cell lineCAL-51
ConcentrationConcentration series: 1 uM, 0.05 nM
Assay / Readoutluminescence / Dmax
Assay IDPGDB_AS000358
PatentWO2026099466A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031227
Compound IDPGDB_C031227
Compound29
Source record IDPGDB_C031227
InChIKeyOXWGVUANMYYDNX-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS000358
Assay family% Degradation
Assay systemcell_based
ReadoutDmax
Technologyluminescence
ConcentrationConcentration series: 1 uM, 0.05 nM
TargetNEK7
E3Not specified
Cell lineCAL-51
OrganismHomo sapiens

Source evidence

Patent IDWO2026099466A1
Compound location

29

29 enlarged structure29 location on patent page 53
Activity table
Page 186 · table start
Page 187 · table end