Activity record

PGDB_A005124

Assay: bindingTarget: KRASQC: ambiguous
Activity overview

IC50 = 1 nM

TargetKRAS
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS000361
PatentWO2026114957A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031999
Compound IDPGDB_C031999
CompoundK-16a;K-16a;K-16a
Source record IDPGDB_C031937
InChIKeyVLCRXFXQEMCCOO-WNWBNICRSA-N

Assay context

Assay IDPGDB_AS000361
Assay familybinding
Assay systembiochemical
ReadoutIC50
TargetKRAS
E3Not specified

Source evidence

Patent IDWO2026114957A1
Compound location

K-16a;K-16a;K-16a

K-16a;K-16a;K-16a enlarged structureK-16a;K-16a;K-16a location on patent page 120
Activity table
Page 155 · table single