Activity record

PGDB_A005674

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 15.8 nM

E3 ligaseCRBN
Cell lineAsPC-1
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000561
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031965
Compound IDPGDB_C031965
CompoundI-25;I-25
Source record IDPGDB_C031965
InChIKeyUFQSYNSLIBSCPS-PHBXMMHKSA-N

Assay context

Assay IDPGDB_AS000561
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineAsPC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-25;I-25

I-25;I-25 enlarged structureI-25;I-25 location on patent page 252
Activity table
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