Activity record

PGDB_A005902

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 1.7 nM

E3 ligaseCRBN
Cell lineLOVO
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000484
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031973
Compound IDPGDB_C031973
CompoundI-33
Source record IDPGDB_C031973
InChIKeyHEXWCPPXWSLRNT-GYFVPHJRSA-N

Assay context

Assay IDPGDB_AS000484
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineLOVO
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-33

I-33 enlarged structureI-33 location on patent page 342
Activity table
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