Activity record

PGDB_A006841

Assay: % DegradationTarget: VAV1QC: ambiguous
Activity overview

DC50 = 40.9 nM

TargetVAV1
Cell lineJurkat
Assay / ReadoutHTRF / DC50
Assay IDPGDB_AS001141
PatentWO2026119120A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C024735
Compound IDPGDB_C024735
Compound51;51
Source record IDPGDB_C024735
InChIKeyVMDUDARWPWUSPT-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001141
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
TechnologyHTRF
TargetVAV1
E3Not specified
Cell lineJurkat
OrganismHomo sapiens

Source evidence

Patent IDWO2026119120A1
Compound location

51;51

51;51 enlarged structure51;51 location on patent page 30
Activity table
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