Activity record

PGDB_A006912

Assay: bindingTarget: KRASQC: ambiguous
Activity overview

IC50 = 2 nM

TargetKRAS
Assay / ReadoutIC50 / binding
Assay IDPGDB_AS001776
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031999
Compound IDPGDB_C031999
CompoundBB-3
Source record IDPGDB_C031999
InChIKeyVLCRXFXQEMCCOO-WNWBNICRSA-N

Assay context

Assay IDPGDB_AS001776
Assay familybinding
Assay systembiochemical
ReadoutIC50
TargetKRAS
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

BB-3

BB-3 enlarged structureBB-3 location on patent page 202
Activity table
Page 309 · table single