Activity record

PGDB_A006928

Assay: viabilityQC: ambiguous
Activity overview

IC50 = 24.9 nM

E3 ligaseCRBN
Cell lineAsPC-1
Assay / ReadoutIC50 / viability
Assay IDPGDB_AS000561
PatentWO2026114958A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C031976
Compound IDPGDB_C031976
CompoundI-36;I-36
Source record IDPGDB_C031976
InChIKeyKGWYXOVJAHNVRU-ZUTXJMHQSA-N

Assay context

Assay IDPGDB_AS000561
Assay familyviability
Assay systemcell_based
ReadoutIC50
Detection target% Cell viability
E3CRBN
Cell lineAsPC-1
OrganismHomo sapiens

Source evidence

Patent IDWO2026114958A1
Compound location

I-36;I-36

I-36;I-36 enlarged structureI-36;I-36 location on patent page 267
Activity table
Page 300 · table start
Page 301 · table end