Activity record

PGDB_A007333

Assay: % DegradationTarget: CDK2QC: standardized
Activity overview

DC50 = 9.6 nM

TargetCDK2
Cell lineHEK293
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001903
PatentWO2025224262A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011769
Compound IDPGDB_C011769
Compound146
Source record IDPGDB_C011769
InChIKeyKNVWWGVIZSEPEL-QTXYGZLBSA-N

Assay context

Assay IDPGDB_AS001903
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
TargetCDK2
E3Not specified
Cell lineHEK293
OrganismHomo sapiens

Source evidence

Patent IDWO2025224262A1
Compound location

146

146 enlarged structure146 location on patent page 22
Activity table
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