Activity record

PGDB_A007393

Assay: % DegradationQC: standardized
Activity overview

IC50 = 0.035 uM

Cell lineMV-4-11
Time7 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001761
PatentWO2020064002A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004159
Compound IDPGDB_C004159
Compound167;167;167
Source record IDPGDB_C021565
InChIKeyUQHOWKIBMUQWSD-UXMRNZNESA-N

Assay context

Assay IDPGDB_AS001761
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time7 d
Detection target% Cell viability
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDWO2020064002A1
Compound location

167;167;167

167;167;167 enlarged structure167;167;167 location on patent page 41
Activity table
Page 198 · table single