Assay

PGDB_AS001761

System: cell_basedCell line: MV-4-11
Assay context summary

Assay context

18 activity records
Assay family% Degradation
Systemcell_based
ReadoutIC50
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens
Detection target% Cell viability
Activity compounds and values

Activity records

18 records
StructureMetricControlRelationValueUnitConcentrationTimeTargetE3Cell linePatentRecord IDCompoundAssayDetails
2D structure for PGDB_C004159
IC50-=0.035uM-—--MV-4-11WO2020064002A1PGDB_A007393PGDB_C004159PGDB_AS001761View
2D structure for PGDB_C004156
IC50-=0.014uM-—--MV-4-11WO2020064002A1PGDB_A007753PGDB_C004156PGDB_AS001761View
2D structure for PGDB_C004161
IC50-=0.017uM-—--MV-4-11WO2020064002A1PGDB_A009063PGDB_C004161PGDB_AS001761View
2D structure for PGDB_C004151
IC50-=0.11uM-—--MV-4-11WO2020064002A1PGDB_A022155PGDB_C004151PGDB_AS001761View
2D structure for PGDB_C004158
IC50-=0.2uM-—--MV-4-11WO2020064002A1PGDB_A024387PGDB_C004158PGDB_AS001761View
2D structure for PGDB_C004152
IC50-=0.57uM-—--MV-4-11WO2020064002A1PGDB_A031608PGDB_C004152PGDB_AS001761View
2D structure for PGDB_C004164
IC50-=0.66uM-—--MV-4-11WO2020064002A1PGDB_A033218PGDB_C004164PGDB_AS001761View
2D structure for PGDB_C004165
IC50-=0.63uM-—--MV-4-11WO2020064002A1PGDB_A035406PGDB_C004165PGDB_AS001761View
2D structure for PGDB_C004163
IC50-=0.48uM-—--MV-4-11WO2020064002A1PGDB_A042941PGDB_C004163PGDB_AS001761View
2D structure for PGDB_C004160
IC50-=0.029uM-—--MV-4-11WO2020064002A1PGDB_A050386PGDB_C004160PGDB_AS001761View
2D structure for PGDB_C008731
% Inhibition->20%-7 d--MV-4-11WO2020064002A1PGDB_A050571PGDB_C008731PGDB_AS001761View
2D structure for PGDB_C004162
IC50-=0.6uM-—--MV-4-11WO2020064002A1PGDB_A052400PGDB_C004162PGDB_AS001761View
2D structure for PGDB_C004153
IC50-=0.18uM-—--MV-4-11WO2020064002A1PGDB_A055605PGDB_C004153PGDB_AS001761View
2D structure for PGDB_C004154
IC50-=0.22uM-—--MV-4-11WO2020064002A1PGDB_A060714PGDB_C004154PGDB_AS001761View
2D structure for PGDB_C001722
% Inhibition->20%-7 d--MV-4-11WO2020064002A1PGDB_A063906PGDB_C001722PGDB_AS001761View
2D structure for PGDB_C004155
IC50-=0.61uM-—--MV-4-11WO2020064002A1PGDB_A066585PGDB_C004155PGDB_AS001761View
2D structure for PGDB_C004151
IC50-=0.51uM-—--MV-4-11WO2020064002A1PGDB_A070436PGDB_C004151PGDB_AS001761View
2D structure for PGDB_C004157
IC50-=0.25uM-—--MV-4-11WO2020064002A1PGDB_A076254PGDB_C004157PGDB_AS001761View
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