Activity record

PGDB_A007497

Assay: % DegradationTarget: IKZF1QC: standardized
Activity overview

DC50 > 30 uM

TargetIKZF1
Cell lineHEK293T
Time24 h
Assay / Readoutfluorescence / DC50
Assay IDPGDB_AS000960
PatentUS20230265071A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C000380
Compound IDPGDB_C000380
Compound1;1
Source record IDPGDB_C000380
InChIKeyUANVSBNJFWFFLB-KKCFVMBUSA-N

Assay context

Assay IDPGDB_AS000960
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyfluorescence
Treatment time24 h
TargetIKZF1
E3Not specified
Cell lineHEK293T
OrganismHomo sapiens

Source evidence

Patent IDUS20230265071A1
Compound location

1;1

1;1 enlarged structure1;1 location on patent page 29
Activity table
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