Activity record

PGDB_A007753

Assay: % DegradationQC: standardized
Activity overview

IC50 = 0.014 uM

Cell lineMV-4-11
Time7 d
Assay / ReadoutIC50 / % Degradation
Assay IDPGDB_AS001761
PatentWO2020064002A1
QC statusstandardized
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C004156
Compound IDPGDB_C004156
Compound158;158;158
Source record IDPGDB_C026725
InChIKeyMRPIWYCYCKIGHP-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001761
Assay family% Degradation
Assay systemcell_based
ReadoutIC50
Treatment time7 d
Detection target% Cell viability
E3CRBN
Cell lineMV-4-11
OrganismHomo sapiens

Source evidence

Patent IDWO2020064002A1
Compound location

158;158;158

158;158;158 enlarged structure158;158;158 location on patent page 40
Activity table
Page 198 · table single