Activity record

PGDB_A008842

Assay: % DegradationTarget: CCNKQC: ambiguous
Activity overview

DC50 < 500 nM

TargetCCNK
Time24 h
Assay / Readoutluminescence / DC50
Assay IDPGDB_AS001864
PatentWO2025245472A1
QC statusambiguous
Evidence details

Compound, assay context, and source

Compound

2D structure for PGDB_C011987
Compound IDPGDB_C011987
Compound121
Source record IDPGDB_C011987
InChIKeyAYQDGDPSFLZNAQ-UHFFFAOYSA-N

Assay context

Assay IDPGDB_AS001864
Assay family% Degradation
Assay systemcell_based
ReadoutDC50
Technologyluminescence
Treatment time24 h
Detection targetprotein_degradation
TargetCCNK
E3Not specified
OrganismHomo sapiens

Source evidence

Patent IDWO2025245472A1
Compound location

121

121 enlarged structure121 location on patent page 148
Activity table
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